The program CHAINSAW from the CCP4 suite,43 guided by the sequence alignment of APH(2)-IVa and APH(2)-IIa, was used to truncate the APH(2)-IIa model such that the conserved residues were retained and nonconserved residues truncated to alanine

The program CHAINSAW from the CCP4 suite,43 guided by the sequence alignment of APH(2)-IVa and APH(2)-IIa, was used to truncate the APH(2)-IIa model such that the conserved residues were retained and nonconserved residues truncated to alanine. higher at pH 6.6) is significantly higher than the being one of the only kinases showing such a propensity.39 […]