These results hold great promise in improving the clinical outcomes of TAM-resistant breast cancer patients
These results hold great promise in improving the clinical outcomes of TAM-resistant breast cancer patients. Acknowledgements Not applicable. Glossary AbbreviationsTAMtamoxifenCAMchorioallantoic membraneDAPI46-diamidino-2-phenylindoleDMEMDulbecco’s modified Eagle’s mediumEDTAethylenediamine tetraacetic acidEGFRepidermal growth factorEMTepithelial to mesenchymal transitionERestrogen receptorFBSfetal bovine serumFGFRfibroblast growth factor receptorIGFRinsulin-like growth factorIL-6interleukin-6JAKJanus kinaseMMP2matrix metalloproteinase-2MMP9matrix metalloproteinase-9MPNmyeloproliferative neoplasmPBSphosphate-buffered salinePDGFRplatelet-derived growth factor receptorRTroom temperatureSDSsodium dodecyl sulfateSTATsignal transducer and activator of transcriptionVEGFvascular […]
of four independent tests
of four independent tests. peritoneal tumor development in immunodeficient mice. Overexpression of GAB2 upregulated the secretion of many chemokines from ovarian cancers cells, including CXCL1, CXCL2 and CXCL8. The secreted chemokines not merely indication through endothelial CXCR2 receptor within a paracrine way to market endothelial pipe formation, but also become autocrine growth elements for GAB2-induced […]