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Scale bar, 5 m. endosomes CY3 where the PS-binding protein EHD1 is recruited to facilitate endosome fission. Our study highlights a novel lipid exchange at ERCendosome MCSs as a nonenzymatic PI4P-to-PS conversion mechanism that organizes membrane remodeling during retrograde membrane trafficking. Introduction Membrane contact sites (MCSs) are sites of direct communication for organelles and the […]